Informacije za studente

Zavod za histologiju i embriologiju



Pročelnik
Prof. dr. sc. Stipan Jonjić, redoviti profesor
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Prof. Stipan Jonjic, MD, PhD Professor and Chairman of the Department for Histology and Embryology
Chair of the Center for Proteomics

Tajnica 
Lidija Karinja
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Zavod za Histologiju i embriologiju
Medicinski fakultet u Rijeci, Braće Branchetta 20, 51000 Rijeka
tel: +385 (0)51 651 170

Studenti se primaju: 
Kancelarija Katedre/Zavoda, PON - PET: 13:00 - 15:00
 


Zavod za histologiju i embriologiju djeluje od 1958. godine od kada datira i kontinuirana organizacija nastave iz histologije i embriologije za studente medicine, stomatologije, kao i studente drugih profila koji se obrazuju na Medicinskom fakultetu. Pored nastave iz histologije i embriologije, članovi katedre vode i organiziraju nastavu na brojnim drugim kolegijima u sklopu dodiplomskih i doktorskih  studija koji se provode na Fakultetu i Sveučilištu. Znanstveno-istraživački rad organiziran je u nekoliko grupa koje rade u području eksperimentalne patologije i imunologije, molekularne biologije i virusologije. Među najvažnija znanstvena dostignuća članova Zavoda ubrajaju se radovi u kojima su karakterizirani imunološki mehanizmi nadzora virusnih infekcija, virusni imuno subverzivni geni, ali i radovi iz područja temeljne imunologije. Znanstvena aktivnost Zavoda vrlo je dobro umrežena u međunarodnu znanstvenu zajednicu s preko 20 suradničkih institucije u zemljama Evrope, Sjedinjenim Američkim Državama, Australiji i Kanadi. Nastavno tome, Zavod za histologiju i embriologiju spada u najprepoznatljivije znanstvene institucije u Hrvatskoj s obzirom na broj i razinu međunarodnih znanstvenih projekata koji se na njemu provode ili su se provodili, kao i prema broju i razini znanstvenih publikacija. Probir i edukacija mladih znanstvenika u sklopu znanstvenih projekata koji se izvode, temeljni je prioritet i Katedre i Zavoda. Većina znanstvenika i nastavnika Zavoda za svoj je rad dobila brojne međunarodne i državne nagrade. Strategija daljnjeg razvoja temelji se na dosadašnjem razvoju, što podrazumijeva aktivnosti na pribavljanju što kvalitetnijih međunarodnih i domaćih znanstvenih projekata, probir najboljih mladih znanstvenika i razvoj novih pravaca istraživanja.
 


Djelatnici:

Pročelnik
 
Prof. dr. sc. Stipan Jonjić, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite.
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Tajnica 
Lidija Karinja, dipl.ing., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 

Prof. dr. sc. Bojan Polić, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Prof. dr. sc. Jelena Tomac, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Prof. dr. sc. Ester Pernjak Pugel, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Prof. dr. sc. Astrid Krmpotić, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Doc.dr.sc. Felix Wensveen, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Doc.dr.sc. Vanda Juranić Lisnić, dipl. ing. biotehnologije, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Dr.sc. Tihana Tršan, dipl.ing.biotehnologije, poslijedoktorandica, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Doc.dr.sc. Berislav Lisnić, dipl. ing. biotehnologije,  e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Mijo Golemac, dr.med., specijalist patologije, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Sali Slavić Stupac, med. lab. inž., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Edvard Ražić, med. lab. inž., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Dr.Branka Popović, dipl.inž.biol., poslijedoktorandica, e-mail:  Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Dr.Vedrana Jelenčić, mag.inž.mol. bioteh., poslijedoktorandica,e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Dr.Maja Lenartić, dipl.ing.molekularne biologije, poslijedoktorandica, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Dijana Rumora , bacc.med.lab.diagn., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Daria Kveštak, mag.biol.mol. – asistent, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Tina Rudančić, bacc.med.lab.diagn. , e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Marko Šestan, dr.med.vet., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Sonja Valentić, mag.biol.mol., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Jelena Železnjak, mag.ing.mol.biotech., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Ana Ćosić, mag.oec.; prof.psihologije,, e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Inga Kavazović, mag.pharm.inv., e-mail: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite. 
Kristina Vuković, mag.biol., email: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite.
 


ZNANSTVENA AKTIVNOST

Popis projekata:

AKTIVNI PROJEKTI:

1.            ''Inflammation and hearing loss following congenital CMV infection''(resubmission), National Institutes of Health (NIH) R01, koordinator William J Britt, University of Alabama at Birmingham, SAD; 2 partnera uključujući MEDRI, Rijeka; 2017. - 2022., USD 3.659.495, MEDRI: USD 229.500
2.             "Strengthening adaptive immunity via innate immunity: enhancing the CD8 T cell response by using the NKG2D ligand expressed in a herpesvirus vector''(StAdvInn), EU FP7 ERC-2012-AdG_20120314-Ideas, PI Stipan Jonjic, 2013 - 2018, EUR 1.754.897
3.             "Congenital CMV and CNS infection mechanisms of protective immunity''National Institutes of Health (NIH) SAD; Grant Number: 1RO1AI089956-01A1; PI William Britt (University of Alabama, Birmingham), co-PI Stipan Jonjic, 2011 - 2016 ~ USD 500.000
4.             "Viral Strategies of Immune Evasion (VISTRIE)'', partners: Luka Cicin-Sain, Melanie Brinkmann (Helmholtz Centre for Infection Research, Braunschweig), Martin Messerle (Medical School Hannover), Ulrich Kalinke (TWINCORE Centre for Experimental and Clinical Infection Research, Hannover), Hartmut Hengel, Anne Halenius (University Hospital Düsseldorf), Stipan Jonjic, 2011 - 2016, EUR 4.500.000
5.             ''Methods for high-throughput glycoproteomic analysis (HTP-GlycoMet)'', (324400) ,FP7 program Marie Curie Actions - Industry-Academia Partnerships and Pathways, coordinator: University of Rijeka, partners: Stipan Jonjić, Faculty of Medicine Rijeka; Genos, Zagreb, Bia Separations, Ajdovščina, Slovenija, Max Planck Society, Magdeburg, Njemačka; 2013 - 2015, EUR 1.818.077,90
6.             ''Platform for trans-Academic Cooperation in Innovation (PACINNO)'', IPA Adriatic CBC Strategic project proposals, coordinator: University of Trieste; 7 partners from the Adriatic region (Stipan Jonjic), 2013-2016, EUR 6.272.300/EUR 636.500
7.             ''Virus-specific Activating NK Cell Receptors and Their Viral Immunoevasion (ViSpeNKRec)'',  Hrvatska zaklada za znanost,voditelj Astrid Krmpotić, 2014.-2018., 991.460,00 KN
8.             ''Centre of Excellence for Research in Viral Immunology and the Development of New Vaccines  (CERVirVac)'', Ministry of Science, Education and Sports of the Republic of Croatia, coordinator Stipan Jonjic (University of Rijeka Faculty of Medicine), partners: Center for Research and Knowledge Transfer in Biotechnology of the University of Zagreband The University Hospital for Infectious Diseases Zagreb, 2014 – 2018
9.             ''A training network for the rational design of the next generation of well-defined glycoconjugate vaccines (GLYCOVAX)'', coordinator: NOVARTIS vaccines and diagnostics  HORIZON 2020,  Marie Sklodowska-Curie Innovative Training Networks, 11 partners including Faculty of Medicine Rijeka, Stipan Jonjic, 2015–2019; 3.560.797,00 EUR/ 247.761,00 EUR
10.             "Mehanizmi prirođene imunosti u razvoju upale visceralnog masnog tkiva i rezistencije na inzulin u debljini", Europski socijalni fond (ESF) – Istraživačke stipendije za profesionalni razvoj mladih istraživača i poslijedoktoranada, voditelj/mentor Bojan Polić, 2015. – 2016., 1.960.612,15 HRK
11.         "The role of pathogen-driven inflammation of visceral adipose tissue in the development of Diabetes Mellitus type II", Unity through Knowledge Fund (UKF), voditelj Bojan Polić, 2013. – 2015., 1.467.000 HRK
12.         "Fat Killers: The role of Natural Killer cells in the development of Diabetes Mellitus type 2",European Foundation for Study of Diabetes (EFSD) – Horizon Programme Grant,  voditelj Bojan Polić, 2013. – 2015., 100.000 EUR



RANIJE FINANCIRANI PROJEKTI (2005. – 2015):

1.      A European Infrastructure of Ligand Binding Molecules Against the Human Proteome, EU FP-6 CA, Akronym: ProteomeBinders, Contract No.:026008), koordinator: Mike Taussig, Babraham Institute, Cambridge, UK, partner: Bojan Polić, 2005. – 2010.
2.      Establishment of high-throughput monoclonal antibody production and hybridoma bank,  FP6-2002-INCO-WBC/SSA-3, 2006.-2008., voditelj: Stipan Jonjić
3.      The role of viral immunoevasins in the pathogenesis of the cytomegalovirus infection., Howard Hughes Medical Institute (HHMI), voditelj: Astrid Krmpotić, 2006. - 2010., USD 650.000
4.       Natural Killer Cell-Mediated Anti-Viral and Anti Tumor Defense and Therapy: Integrated research training in molecular medicine, bioinformatics and issues of biotech patents and SME business., Marie Curie Research Training Networks koordinator: E. Hofer, Medical University of Vienna, Austrija, 2006.-2009., partner: Stipan Jonjić
5.      Razvoj sustava za proizvodnju biomarkerom obilježenih antitijela (02-04 NZZ) odobrenog u okviru programa Partnerstvo u istraživanjima Nacionalne zaklade za znanost, visoko obrazovanje i tehnologijski razvoj Republike Hrvatske, voditelj: Bojan Polić, 2006. - 2009.
6.      Transcriptomic Approach to Viral Disease Research, Fond Jedinstvo uz pomoć znanja (UKF), voditelji projekta: Joanne Trgovcich - The Ohio State University, Columbus Ohio, SAD i Stipan Jonjić, 2007.-2010., EUR 106.415
7.      Funkcija NK staničnog receptora NKp46 u nadzoru infekcije citomegalovirusom i virusom influence, Hrvatsko-Izraelski zajednički istraživački program, voditelji:  Stipan Jonjić i Ofer Mandelboim, Hadassah Medical School, The Hebrew University Jerusalem, Izrael, 2009. - 2011., USD 100.000
8.      Impact of NKG2D-deficiency on the Immunosurveillance of Cytomegalovirus and West Nile Virus Infections, Hrvatsko-Izraelski zajednički istraživački program, voditelji: Bojan Polic i Angel Porgador, Ben Gurion University of the Negev, Izrael, 2009. - 2010., USD 100.000
9.      Razvoj modela za terapiju virusnih infekcija povezivanjem urođene i stečene imunosti pomoću fuzijskih proteina,  Nacionalna zaklada za znanost, visoko školstvo i tehnologijski razvoj Republike Hrvatske,  voditelj: Stipan Jonjic, 2008.-2011., EUR 105.000 (NZZ) + EUR 45.000 Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru.MZOŠ (062-0621261-1263), voditelj: Stipan Jonjić,  2007.-2011. EUR 102.740
10.  Uloga NKG2D u razvoju, homeostazi i efektorskim funkcijama imunološkog sustava. MZOŠ (062-0621261-1271), voditelj Bojan Polić, 2007. - 2012.
11.  Uloga  imunosubverzivnih citomegalovirusnih gena u latenciji. MZOŠ (062-0621261-1268), voditelj: Astrid Krmpotić, 2007. - 2012.
12.  Perinatalni citomegalovirusni encefalitis. MZOŠ (062-0621261-1269), voditelj Ester Pernjak Pugel,  2007. - 2012.
13.  Citomegalovirusna infekcija ovarija. MZOŠ (062-0621261-1265), voditelj: Jelena Tomac, 2007. - 2012.
14.  The Center for Antibody Production Rijeka: Upgrading the Central Research and Service Infrastructure for South Eastern Region of Europe. EU FP7-REGPOT-2008-1, voditelj: Stipan Jonjić, 2009.-2012., EUR 619.770
15.  Viral evasion of NK cells. National Institutes of Health (NIH) SAD, Grant Number: 1RO1AI083201-01 , voditelj: Stipan Jonjic, 2009.-2013., USD 270.249
16.  MCMV Infection of the Developing CNS: Neuroinvasion and immune Control. National Institutes of Health (NIH) USA; Grant Number: 1R01NS065845 -01, voditelji: William Britt (University of Alabama, Birmingham), Stipan Jonjic (Department of Histology and Embryology – Faculty of Medicine, University of Rijeka),  2010. – 2015., ~ USD 350.000
17.  Upgrading the capacities for research in translational medicine at the Faculty of  Medicine University of Rijeka (TransMedRi - 256686), EU FP7-REGPOT-2010-5. Stipan Jonjic, zajedno s kolegama s Medicinskog fakulteta uključujući S.Volarevića, M. Abram, T.Rukavinu, A.Gerbin i nekolicinu drugih radio je na pripremi projekta. Radi se o institucionalnom projektu koordiniranog od strane Prodekana za znanost Medicinskog fakulteta B.Polića, koji ima za cilj povećati istraživački potencijal fakulteta za translacijsko istraživanje u medicini, napose na polju infektivnih oboljenja. 2010. – 2013.,  EUR 1.853.941
18.  Uloga cistatina u imunološkom odgovoru na viruse. Znanstveno tehnološka suradnja sa Republikom Slovenijom - partneri sufinanciranja MZOŠ (001.10-1264); voditelj Nataša  Kopitar-Jerala, Institut Jožef Štefan, Ljubljana, suistraživač: Stipan Jonjić, 2012. - 2013., EUR 2.200
19.  NKG2D in T-cells - Memory Control; The role of NKG2D and the T-cell receptor in memory T cell biology. (projekt EU FP7 People-2010-IEF, Acronym: NKG2D and T cells, No: 274995, poslijedoktorsko usavršavanje: Dr. Felix M. Wensveen, koordinator: Bojan Polić; 2011. – 2013.; 178.000 EUR
20.  Becoming entrepreneurial: knowledge transfer from the University of Rijeka Faculty of Medicine to the biotechnology business sector.,Instrument for Pre- accession Assistance – IPA, voditelj: Stipan Jonjic, partner Martin Messerle, 2013. – 2015., 440.000 EUR
21.  Immunosurveillance mechanisms of herpesvirus infection  and development of new virus vaccines and vaccine vectors, University of Rijeka, Uniri projects/516, voditelj: Stipan Jonjić, 2013. – 2014., 167.367,54 KN

 



POPIS NAJVAŽNIJIH PUBLIKACIJA U PERIODU 2005. – 2015.  
 
1.             Lisnic B, Juranic Lisnic V, Jonjic S: NK cell interplay with cytomegaloviruses, Current Opinion in Virology, 15:9–18;2015
 
2.             Bradford R,  Yoo Y, Golemac M,  Pugel E,  Jonjic S,  Britt WJ: Murine CMV-Induced Hearing Loss Is Associated with Inner Ear Inflammation and Loss of Spiral Ganglia Neurons, PLoS Pathogens, 11(4): e1004774. doi:10.1371/journal.ppat.1004774; 2015
 
3.             Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, Enk J, Bar-On Y, Stanietsky-Kaynan N, Coppenhagen-Glazer S, Shussman N, Almogy G, Cuapio A, Hofer E, Mevorach D, Tabib A, Ortenberg R, Markel G, Miklic K, Jonjic S, Brennan CA, Garrett WS, Bachrach G, Mandelboim O: Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack.Immunity,42(2):344-55; 2015
 
4.             Lemmermann N, Krmpotic A, Podlech J, Brizic I,  Prager A,  Adler H, Karbach A, Wu Y, Jonjic S, Reddehase MJ, Adler B: Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread. PLoS Pathogens, doi:10.1371/journal.ppat.1004640; 2015
 
5.             Deng W, Gowen BG, Zhang L, Wang L, Lau S, Iannello A, Xu J, Rovis TL, Xiong N, Raulet DH: Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection. Science 348(6230):136-9; 2015
 
6.             Wensveen FM, Jelenčić V, Valentić S, Šestan M, Wensveen TT, Theurich S, Glasner A, Mendrila D, Štimac D, Wunderlich FT, Brüning JC, Mandelboim O, Polić B: NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nature Immunology,16:376-385; 2015
 
7.             Trsan T, Busche A, Abram M, Wensveen FM, Lemmermann NA, Arapovic M, Babic M,Tomic A, Golemac M, Brinkmann MM, Jäger W, Oxenius A, Polic B, Krmpotic A, Messerle M, Jonjic S: Superior induction and maintenance of protective CD8 T cells in mice infected with MCMV vector expressing RAE-1γ. Proceedings of the National Academy of Sciences of the United States of America, 110(41):16550-5; 2013
 
8.             Juranic Lisnic V, Babic Cac M, Lisnic B, Trsan T, Mefferd A, Mukhopadhyay CD, Cook CH, Jonjic S, Trgovcich J: Dual Analysis of the Murine Cytomegalovirus and Host Cell Transcriptomes Reveal New Aspects of the Virus-Host Cell Interface.PLoS Pathogens, 9(9):e1003611. doi: 10.1371/journal.ppat.1003611; 2013
 
9.           Wensveen MF, Lenartic M, Jelencic V,  Lemmermann AN,  ten Brinke A, Jonjic S, Polic   B: NKG2D Induces Mcl-1 Expression and Mediates Survival of CD8 Memory T Cell Precursors via Phosphatidylinositol 3-Kinase. doi:10.4049/jimmunol.1300670, Journal of Immunology,  191(3):1307-15; 2013
 
10.         Jordan S, Ruzsics Z, Mitrovic M, Baranek T, Arapovic J, Krmpotic A, Vivier E, Dalod M, Jonjic S, Döelken L, Koszinowski UH: Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection. Cell Host & Microbe, 13, 535-545; 2013
11.         Lenac Rovis T, Bailer SM, Pothineni VR, Ouwendijk WJ, Simic H, Babic M, Miklic K, Malic S, Verweij MC, Baiker A, Gonzalez O, von Brunn A, Zimmer R, Früh K,Verjans GM, Jonjic S, Haas J.:A comprehensive analysis of varicella zoster virus proteins using a new monoclonal antibody collection. Journal of Virology, 87(12):6943-6954; 2013
12.         Lankry D, Lenac Rovis T, Jonjic S, Mandelboim O:The interaction between CD300a and Phosphatidylserine inhibits tumor cell killing by NK cell. European Journal of Immunology, doi: 10.1002/eji.201343433; 2013
13.         Kosmac K, Bantug R, Pugel E, Cekinovic Dj, Jonjic S, Britt W: Glucocorticoid Treatment of MCMV Infected Newborn Mice Attenuates CNS Inflammation and Limits Deficits in Cerebellar Development (PPATHOGENS-D-12-02090R1) PLoS Pathogens, 9(3): e1003200; 2013
14.         Wensveen FM, Klarenbeek PL, van Gisbergen K, Pascutti MF, Derks I, van Schaik B, ten Brinke A, de Vries N, Cekinovic D, Jonjic S, van Lier R,Eldering E: Pro-Apoptotic Protein Noxa Regulates Memory T Cell Population Size and Protects against Lethal Immunopathology. Journal of Immunology, 190(3):1180-91; 2013
15.         van Gisbergen K, Kragten N, Hertoghs K , WensveenF, Jonjic S, Hamann J, Nolte M,van Lier R: Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation. Nature Immunology, 13(9):864-71; 2012
16.         Mandaric S, Walton S, Ruelicke T, Richter K, Girard-Madoux M, Clausen B, Zurunic A, Kamanaka M, Flavell R, Jonjic S, Oxenius A: IL-10 Suppression of NK/DC Crosstalk Leads to Poor Priming of MCMV-Specific CD4 T Cells and Prolonged MCMV Persistence. PLoS Pathogens, 8(8):e1002846; 2012
17.         Mitrovic M, Arapovic J, Jordan S, Fodil-Cornu N, Ebert S, Vidal SM, Krmpotic A, Reddehase MJ, Jonjic S: The NK-cell response to mouse cytomegalovirus infection affects the level and kinetics of the early CD8+ T-cell response.Journal of Virology, 86(4):2165-75; 2012
18.         Marcinowski L, Tanguy M, Krmpotic A, Rädle B, Juranic Lisnic V, Tuddenham L, Chane-Woon-Ming B, Ruzsics Z, Erhard F, Benkartek C, Babic M, Zimmer R, Trgovcich J, Koszinowski U, Jonjic S, Pfeffer S, Dölken L: Degradation of cellular miR-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo. PLoS Pathogens, 8(2): e1002510; 2012
19.         Markiewicz MA, Wise EL, Buchwald ZS, Pinto AK, ZafirovaB, Polic B, Shaw AS: Antigen-independent recruitment of CTL to pancreatic islets expressing an NKG2D ligand. Immunity, 36:132-141; 2012
20.         Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Polic B, Al-Harthi L, Sperling AI and Guevara-Patino JA. : NKG2D signaling on CD8(+) T cells represses T-bet and rescues CD4-unhelped CD8(+) T cell memory recall but not effector responses. Nature Medicine, 18:422-428; 2012
21.         Babic M, Krmpotic A, Jonjic S: All is fair in virus-host interactions: NK cells and cytomegalovirus.Trends in Molecular Medicine,17(11):1471-4941; 2011
22.         Pyzik M, Charbonneau B, Gendron-Pontbriand EM, Babic M, Krmpotic A, Jonjic S, Vidal S: Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains. Journal of Experimental Medicine, 208(5):1105-17; 2011
23.         Jovanovic I, Radosavljevic G, Mitrovic M, Lisnic Juranic V, McKenzie A, Arsenijevic N, Jonjic S, Lukic M: ST2 Deletion Enhances Innate and Acquired Immunity to Murine Mammary Carcinoma. European Journal of Immunology, 41:7,1902-1912; 2011
24.         Strid J, Sobolev O, Zafirova B, Polic B, Hayday A:  The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science,334(6060):1293-7;2011
25.         Slavuljica I, Busche A, Babic M, Mitrovic M, Gasparovic I, Cekinovic Dj, Markova Car E, Pernjak Pugel E, Cikovic A, Juranic Lisnic V, Britt WJ, Koszinowski U, Messerle M, Krmpotic A, Jonjic S: Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties.Journal of Clinical Investigation,120(12):4532-45; 2010
26.         Babic M, Pyzik M, Zafirova B, Mitrovic M, Butorac V, Lanier LL, Krmpotic A, Vidal SM, Jonjic S: Cytomegalovirus immunoevasin reveals the physiological role of ''missing self'' recognition in NK cell dependent virus control in vivo. Journal of Experimental Medicine,207(12):2663-2673; 2010
27.         Doelken L, Krmpotic A, Koethe S, Tuddenham L, Tanguy M, Marcinowska L, Ruzsics Z, Elefant N, Altuvia Y, Margalit H, Koszinowski U, Jonjic S, Pfeffer S: Cytomegalovirus microRNAs facilitate persistant virus infection in salivary glands. PloS Pathogens, 14;6(10):e1001150; 2010
28.         Juranic Lisnic V, Krmpotic A, Jonjic S: Modulation of natural killer cell activity by viruses. Current Opinion in Microbiology, 13:1-10; 2010
29.         Stanietsky N, Simic H, Arapovic J, Toporik A, Levy O, Novik A, Levine Z, Beiman M, Dassa L, Achdout H, Stern-Ginossar N, Tsukerman P, Jonjic S, Mandelboim O: The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America, 106(42):17858-63; 2009
30.         Arapovic J, Lenac T, Antulov R, Polic B, Ruzsics Z, Carayannopoulos LN, Koszinowski UH, Krmpotic A, Jonjic S: Differential susceptibility of RAE-1 isoforms to mouse cytomegalovirus. Journal of Virology, 83(16):8198-207; 2009
31.         Zafirova B, Mandaric S, Antulov R, Krmpotic A, Jonsson H, Yokoyama WM, Jonjic S, Polic B: Altered NK cell development and enhanced NK cell-mediated resistance to mouse cytomegalovirus in NKG2D-deficient mice. Immunity,31(2):270-82; 2009
32.         Kielczewska A, Pyzik M, Sun T, Krmpotic A, Lodoen MB, Munks MW, Babic M, Hill AB, Koszinowski UH, Jonjic S, Lanier L,Vidal S: Ly49P recognition of cytomegalovirus-infected cells expressing H2-Dk and CMV-encoded m04 correlates with the NK cell antiviral response. Journal of Experimental Medicine, 206(3):515-23; 2009
33.         Cekinovic D, Golemac M, Pugel EP, Tomac J, Cicin-Sain L, Slavuljica I, Bradford R, Misch S, Winkler TH, Mach M, Britt WJ, Jonjic S: Passive immunization reduces MCMV induced brain pathology in newborn mice. Journal of Virology, 82(24):12172-80; 2008
34.         Jonjic S, Babic M, Polic B, Krmpotic A: Immune evasion of natural killer cells by viruses. Current Opinion in Immunology, 20(1):30-8; 2008
35.         Koontz T, Bralic M, Tomac J, Pernjak-Pugel E, Bantug G, Jonjic S, and Britt W J: Altered Development of the Brain after Focal Herpesvirus Infection of the CNS. Journal of Experimental Medicine, 205(2):423-35; 2008
36.         Lenac T, Budt M, Arapovic J, Hasan M, Zimmermann A, Simic H, Krmpotic A, Messerle M, Ruzsics Z, Koszinowski UH, Hengel H, Jonjic S: The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.Journal of Experimental Medicine, 203(8):1843-50; 2006
37.         Krmpotic A, Hasan M, Loewendorf A, Saulig T, Halenius A, Lenac T, Polic B, Bubic I, Kriegeskorte A, Pernjak Pugel E, Messerle M, Hengel H, Busch D, Koszinowski UH, Jonjic S: NK cell activation through the NKG2D ligand Mult-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145. Journal of Experimental Medicine, 201(2):211-220; 2005
38.         Hasan M, Krmpotic A, Ruzsics Z, Bubic I, Lenac T, Halenius A, Loewendorf A, Messerle M, Hengel H, Jonjic S, Koszinowski UH: Selective down-regulation of the NKG2D ligand H60 by mouse cytomegalovirus m155 glycoprotein. Journal of Virology, 79(5):2920-2930; 2005